Dr Pappuu Rajasekkhar - Orthopaedic and Joint replaement, Trauma, Ilizaorov, Diabetic foot specialist

Bone infections after fractures—known as Fracture-Related Infections (FRIs)—occur when bacteria contaminate the bone site. This usually happens during an open fracture or surgical repair. Symptoms include persistent, worsening pain, severe swelling, redness, warmth, or pus drainage. Treatment almost always requires a combination of surgery and antibiotics. Key Details & Symptoms • How it happens: Bacteria (most commonly Staphylococcus aureus) enter the wound during an open fracture or are introduced during surgical placement of metal plates or screws. • Primary warning signs: Severe, unexpected pain, warmth, redness, and swelling around the injury site. • Drainage: Persistent, worsening wound drainage or a pus pocket that bursts. • Systemic symptoms: Chills, night sweats, and persistent fever. • Risk factors: Severe soft tissue damage, open fractures, diabetes, compromised immune systems, and smoking. Diagnosis • Physical & Clinical exam: Orthopedic surgeons check for systemic signs (fever) and localized inflammation. [1] • Tissue sampling: Surgeons often take deep tissue samples or perform a swab during surgery to identify the exact bacteria causing the infection. Imaging & bloodwork: X-rays, White Blood Cell (WBC) scintigraphy, and blood tests for inflammatory markers help confirm the diagnosis and assess bone health Treatment & Management • Surgery: Multiple surgeries are frequently required to wash out the area, place antibiotic delivery systems (like "antibiotic beads" Jun 25, 2026